Herbs in The Formula
We meticulously find the best quality herbs and only use those that were tested for pesticide residues, heavy metals and verified for authenticity. The following herbs are used for the Formula for Pain (both the cream and the spray) and The Formula for Cramps (when noted in parenthesis). Additionally, studies on the pharmacological actions of the herbs are noted below as well.
Frankincense and Myrrh resin
AKA: Mo yao and Ru xiang
How it helps123
Corydalis (in the Pain and Cramps Formula)
AKA: Yan hu suo
How it helps4
Homalomena
AKA: Qian nian jian
How it helps 56
Paniculate Swallowwort
AKA: Xu chang qing
How it helps7 8
Clematidis
AKA: Wei ling xian
How it helps9
Chinese Knotty Pine
AKA: Song jie
How it helps10
Star Jasmine Stem
AKA: Luo shi tengHow it helps11 12
Sichuan Pepper (In both the Pain and Cramps Formula)
AKA: Hua jiao
How it helps131
Drynaria
AKA: Gu sui BuHow it helps 15
Safflower (In both the Pain and Cramps Formula)
AKA: Hong hua
How it helps16
Angelica (In both the Pain and Cramps Formula)
AKA: Dang gui wei
How it helps17
Dispacis
AKA: Xu duan
How it helps18 19
Skullcap
AKA: Huang qin
How it helps20
Motherwort (Cramps Formula only)
AKA: Yi mu caoHow it helps21
Reduces Uterine Spasms
Artemisia (Cramps Formula Only)
AKA: Ai Ye
How it helps22 23
Sappan Wood (Cramps Formula Only)
AKA: Su Mu
How it helps24
Licorice (Cramps Formula Only)
AKA: Gan Cao
How it helps25 26
Wild Angelica (Cramps Formula Only)
AKA: Bai Zhi
How it helps27
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[2] Local anaesthetic, antibacterial and antifungal properties of sesquiterpenes from myrrh. | DrugBank Online. Accessed November 3, 2021. https://go.drugbank.com/articles/A19618
[3] Cheng YW, Cheah KP, Lin CW, et al. Myrrh mediates haem oxygenase-1 expression to suppress the lipopolysaccharide-induced inflammatory response in RAW264.7 macrophages. J Pharm Pharmacol. 2011;63(9):1211-1218. doi:10.1111/j.2042-7158.2011.01329.x
[4] Corydalis - an overview | ScienceDirect Topics. Accessed November 3, 2021. https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/corydalis
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[12] Sheu MJ, Chou PY, Cheng HC, et al. Analgesic and anti-inflammatory activities of a water extract of Trachelospermum jasminoides (Apocynaceae).J Ethnopharmacol.2009;126(2):332-338. doi:10.1016/j.jep.2009.08.019
[13] Wu G, Wu H. Analgesia Synergism of Essential Oil from Pericarp ofZanthoxylum schinifoliumand Verapamil.Evid Based Complement Alternat Med.2014;2014:1-8. doi:10.1155/2014/505876
[14] Lan Y, Li H, Chen Y yan, et al. Essential oil from Zanthoxylum bungeanum Maxim. and its main components used as transdermal penetration enhancers: a comparative study.J Zhejiang Univ Sci B.2014;15(11):940-952. doi:10.1631/jzus.B1400158
[15] Sun JS, Lin CY, Dong GC, et al. The effect of Gu-Sui-Bu (Drynaria fortunei J. Sm) on bone cell activities.
Biomaterials. 2002;23(16):3377-3385. doi: 10.1016/S0142-9612(02)00038-8
[16] Delshad E, Yousefi M, Sasannezhad P, Rakhshandeh H, Ayati Z. Medical uses of Carthamus tinctorius L. (Safflower): a comprehensive review from Traditional Medicine to Modern Medicine.Electron Physician.2018;10(4):6672-6681. doi:10.19082/6672
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[18] Park JY, Park SD, Koh YJ, Kim DI, Lee JH. Aqueous extract of Dipsacus asperoides suppresses lipopolysaccharide-stimulated inflammatory responses by inhibiting the ERK1/2 signaling pathway in RAW 264.7 macrophages.J Ethnopharmacol.2019;231:253-261. doi:10.1016/j.jep.2018.11.010
[19] Chang NJ, Chen YW, Shieh DE, Fang HY, Shie MY. The effects of injectable calcium silicate-based composites with the Chinese herb on an osteogenic accelerator in vitro.
Biomed Mater.
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doi:10.1088/1748-6041/10/5/055004
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[21] Juan Liu, Cheng Peng, Qin-Mei Zhou, Li Guo, Zhao-Hua Liu, Liang Xiong, Alkaloids and flavonoid glycosides from the aerial parts of Leonurus japonicus and their opposite effects on uterine smooth muscle, Phytochemistry, Volume 145, 2018, Pages 128-136, ISSN 0031-9422
[22] Adams JD Jr. The Use of California Sagebrush (Artemisia californica) Liniment to Control Pain. Pharmaceuticals. 2012; 5(10):1045-1053.
[23] Liu, J., Xiong, P., Huang, L., Zhang, W., Song, L., Hu, H., Jia, B., & Liu, X. (2023). Artemisia anomala S. Moore: A review of botany, traditional uses, phytochemistry, pharmacology and quality control. Journal of ethnopharmacology, 315, 116663.
[24] Saptarini, Nyi & Deswati, Dytha. (2021). Analgesic and Antipyretic Activities of Ethanolic Extract of Sappan wood (Caesalpinia sappan L.) Leaves. Research Journal of Pharmacy and Technology.
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